Feb. 27, 2020, 2:11 p.m.
Faculty Seminar: Ivo Sbalzarini - New computing enables new biology, which inspires new computing.
On behalf of the Dean of the Faculty, we invite employees and students to the faculty seminar, which will take place on Tuesday 3rd March at 12:30 at the Institute of Computer Science, Hall 25.
The speaker will be prof. Ivo Sbalzarini (TU Dresden) and the title of his talk is New computing enables new biology, which inspires new computing
Before the seminar, at 12:00, coffee and cookies will be served.
Development and morphogenesis of tissues, organs, and embryos emerges from the
collective self-organization of cells that communicate though chemical and
mechanical signals. Decisions about growth, division, and migration are taken
locally by each cell based on the collective information. In this sense, a
developing tissue is akin to a massively parallel computer system, where each
cell or processor computes robust local decisions, integrating communication
with other cells/processors. Mechanistically understanding and reprogramming
this system is a grand challenge. Our vision is to develop a virtual computer
model of a developing embryo, incorporating the known biochemistry and
biophysics into a computational model in 3D-space and time, in order to
understand the information-processing aspects of development on an algorithmic
basis. While the “hardware” (proteins, lipids, etc.) and the “source code”
(genome) are increasingly known, we known virtually nothing about the algorithms
that this code implements on this hardware. Using examples from our work, I
highlight computational challenges along the way. These range from
content-adaptive data representations for machine learning, to novel languages
for parallel high-performance computing, to virtual reality and real-time
visualization for 3D microscopy and numerical simulations of biochemical and
biomechanical models. This cooperative interdisciplinary effort contributes to
all involved disciplines.
Ivo Sbalzarini is the Chair of Scientific Computing for Systems Biology on the
faculty of computer science of TU Dresden, a professor of mathematics at TU
Dresden, and director of the TUD-Department in the Center for Systems Biology
Dresden. He also is a permanent Senior Research Group Leader with the Max Planck
Institute of Molecular Cell Biology and Genetics in Dresden. He graduated in
Mechanical Engineering from ETH Zurich in 2002 (Willi Studer Award). He
completed his doctorate in computer science in 2006 at ETH Zurich (Chorafas
Award, Weizmann Institute of Science), where he formed a close collaboration
between biology and computer science. In 2006, he was named Assistant Professor
for Computational Science in the Department of Computer Science of ETH Zurich.
In 2012, Ivo and his group moved to Dresden, where he became one of the founding
members of the new Max Planck Center for Systems Biology and the TU-Dresden
Chair of Scientific Computing for Systems Biology. He also serves as a research
avenue leader in the Federal Cluster of Excellence “Physics of Life", Dean of
the International Max Planck Research School in Cell, Developmental, and Systems
Biology, Vice-Dean of the Faculty of Computer Science, and he is a member of the
board of directors of the CASUS Institute in Görlitz.